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Castleman's disease: A rare case report of unicentric type in a young female
Manpreet S Salooja1, Kishore C Mukherjee1, Harpreet Khetrapal2, Kavita Srivastava3, Kiran Patil4, Ashish Gupta5, Kavita Chhabra4, Akhil Bassi6
1 Department of Cardiovascular and Thoracic Surgery, SPS Hospitals, Ludhiana, Punjab, India
2 Department of Surgery, SPS Hospitals, Ludhiana, Punjab, India
3 Department of Pathology, SPS Hospitals, Ludhiana, Punjab, India
4 Department of Anaesthesia, SPS Hospitals, Ludhiana, Punjab, India
5 Department of Plastic Surgery, SPS Hospitals, Ludhiana, Punjab, India
6 Department of Cardiac Surgery, SPS Hospitals, Ludhiana, Punjab, India
Correspondence Address:
Manpreet S Salooja
Department of Cardiovascular and Thoracic Surgery, SPS Hospitals, Sherpur Chowk, Ludhiana - 141 001, Punjab
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/2320-3846.175212
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Castleman's disease (CD), or angiofollicular lymph node hyperplasia, is a relatively rare disorder characterized by the benign proliferation of lymphoid tissue. Two clinical entities have been described: A unicentric presentation with the disease confined to a single anatomic lymph node and a multicentric presentation characterized by generalized lymphadenopathy and a more aggressive clinical course. In addition, three histopathological subtypes have been described: Hyaline-vascular (80–90%), plasma cell (10–20%), and a mixed variant. Preoperative diagnosis of CD is difficult, and the definitive result is based on postoperative pathological findings. The gold standard therapy for unicentric type is the complete surgical excision. Overall prognosis is good, particularly in the unicentric variety of disease. We report a case of 22-year-old female presenting with a large subpectoral mass on left side chest wall below clavicle. It was painless and gradually increasing since 6 months. |
